cost-effectiveness evaluation of quadrivalent human papilloma virus vaccine for hpv-related disease in iran

نویسندگان

mohsen khatibi

hamid reza rasekh department of pharmacoeconomics and pharmaceutical administration, faculty of pharmacy, shahid beheshti university of medical sciences, tehran, iran

zohreh shahverdi department of obstetrics & gynecology, shahid beheshti university of medical sciences, tehran, iran

hamid reza jamshidi department of pharmacology, shahid beheshti university of medical sciences, tehran, iran

چکیده

human papilloma virus (hpv) vaccine recently has been added to the iran drug list, decision makers need information beyond that available from rcts to recommend funding for this vaccination program to add it to the national immunization program in iran. modeling and economic studies have addressed some of those information needs in foreign countries. in order to determine the long term benefit of this vaccine and impact of vaccine program on the future rate of cervical cancer in iran, we described a model, based on the available economic and health effects of human papilloma virus (hpv), to estimate the cost-effectiveness of hpv vaccination of 15-year-old girls in iran. our objective is to estimate the cost-effectiveness of hpv vaccination in iran against cervical cancer based on available data; incremental cost-effectiveness ratio (icer) calculations were based on a model comparing a cohort of 15-year-old girls with and without vaccination. we developed a static model based on available data in iran on the epidemiology of hpv related health outcome. the model compared the cohort of all 15-year old girls alive in the year 2013 with and without vaccination. the cost per qaly, which was found based on our assumption for the vaccination of 15-years old girl to current situation was 439,000,000 iranian rial rate (irr). by considering the key parameters in our sensitivity analysis, value varied from 251,000,000 irr to 842,000,000 irr. in conclusion, quadrivalent hpv vaccine (gardasil) is not cost-effective in iran based on the base-case parameters value.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Cost-Effectiveness Evaluation of Quadrivalent Human Papilloma Virus Vaccine for HPV-Related Disease in Iran

Human Papilloma Virus (HPV) vaccine recently has been added to the Iran Drug List, decision makers need information beyond that available from RCTs to recommend funding for this vaccination program to add it to the National Immunization program in Iran. Modeling and economic studies have addressed some of those information needs in foreign countries. In order to determine the long term benefit ...

متن کامل

Cost-Effectiveness Evaluation of Quadrivalent Human Papilloma Virus Vaccine for HPV-Related Disease in Iran

Human Papilloma Virus (HPV) vaccine recently has been added to the Iran Drug List, decision makers need information beyond that available from RCTs to recommend funding for this vaccination program to add it to the National Immunization program in Iran. Modeling and economic studies have addressed some of those information needs in foreign countries. In order to determine the long term benefit ...

متن کامل

Cost-Effectiveness Evaluation of Quadrivalent Human Papilloma Virus Vaccine for HPV-Related Disease in Iran

Human Papilloma Virus (HPV) vaccine has been added recently to the Iran Drug List. So, decision makers need information beyond that available from RCTs to recommend funding for this vaccination program to add it to the National Immunization program in Iran. Modeling and economic studies have addressed some of those information needs in foreign countries. In order to determine the long term bene...

متن کامل

Quadrivalent HPV vaccine efficacy against disease related to vaccine and non-vaccine HPV types in males.

A small number of HPV types are related to a majority of HPV-related neoplastic lesions in humans. High-risk types such as HPV 16 and 18 are most often implicated, although other oncogenic and non-oncogenic HPV types can cause disease in men. The efficacy of the quadrivalent HPV vaccine (qHPV) against external genital lesions and intra-anal disease related to HPV in men has been demonstrated. T...

متن کامل

Applying a Simple Model of Cost Effectiveness Study of HPV Vaccine for Iran

HPV vaccine has been recently added to the Iran Drug List, so decision makers need information beyond that available from RCTs to recommend funding for this vaccination. Modeling and economic studies have addressed some of those information needs. We reviewed cost effectiveness studies to find a suitable model for Iranian population to determine the potential cost effectiveness of HPV vaccine p...

متن کامل

Applying a Simple Model of Cost Effectiveness Study of HPV Vaccine for Iran

HPV vaccine has been recently added to the Iran Drug List, so decision makers need information beyond that available from RCTs to recommend funding for this vaccination. Modeling and economic studies have addressed some of those information needs. We reviewed cost effectiveness studies to find a suitable model for Iranian population to determine the potential cost effectiveness of HPV vaccine p...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of pharmaceutical research

جلد ۱۳، شماره Supplement، صفحات ۲۲۵-۲۳۴

کلمات کلیدی

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023